Atypical pneumonia coverage
Empirical antibiotics for CAP, 大部分的guideline建議需要atypical and typical pneumonia的抗菌涵蓋能力。有證據例嗎？沒有！
Empiric antibiotic coverage of atypical pathogens for community acquired pneumonia in hospitalized adults.Cochrane Database Syst Rev. 2008 Jan 23;(1):CD004418.
大部分guideline建議：
Suggested regimens include extended spectrum cephalosporins, beta-lactams (BL) or beta-
lactam/beta-lactamase inhibitors (BL/BLI), all combined with macrolides, or a single agent with broad coverage, i.e. fluoroquinolones.
那些藥物歸類於atypical pneumonia coverage?
Regimens containing the following drugs,were considered atypical
coverage:
1. Macrolides: including erythromycin, roxithromycin, azithromycin, clarithromycin.
2. Fluoroquinolone: including ciprofloxacin, ofloxacin, levofloxcin, trovafloxacin, moxifloxacin, grepafloxacin.
3. Tetracyclines, including tetracycline, doxycycline, tigecycline, minocycline.
4. Chloramphenicol.
5. Streptogramins, including pristinamycin, and quinupristin-dalfopristin.
最常見的atypical patho-organisms:
Legionella pneumophilae (L. pneumophilae),
Mycoplasma pneumoniae (M. pneumoniae)
Chlamydia pneumoniae (C. pneumoniae))
常見菌種：
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