歲月麻醉

Anesthesia,Joyful Life
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麻醉與毒品

所有市面上拿得到的毒品,含四級管制藥(安眠鎮靜劑),都是麻醉用藥!所謂藥是三分毒,對麻醉藥而言,藥即是毒,端看『誰』在使用這個藥物!

倒趴床上猝死 疑「玩大象」惹禍

「治得舒」這個看起來面生得新鮮的藥物是誰呢?喔!竟然是取代停產pentothrol的Thiamylal(citosol),哇!外面毒品市場也跟醫界同步喔!同樣歸屬在barbiturates類。這個也可以用來作為解癮的替代藥物?!是不是嗎啡太缺貨,不然就是經濟不景氣,只好將就將就。這種東西,對於中樞神經的作用是非常短暫,一般起效時間只有one-arm-to-brain,小於1分鐘,然後就重分佈於身體其他組織,主要是脂肪,肌肉等,時間,只有5-10分鐘,這個沒有欣快感,只有茫茫的作用,有點像宿醉的感覺,因此,很容易就打過量,結果就是呼吸循環抑制,猝死!

毒品與麻醉既然這樣密切的關係,那麻醉醫師在解癮這塊領域,是否能缺席呢?目前主流還是在精神科醫師,不過,彼此側重的領域不同,前者在physical, 後者在psychological,ultra-rapid detoxification 也是麻醉科在做,全世界用最多的嗎啡代替物,methadone,其他戒毒藥物,buprenorphine,Suboxone(buprenorphine 與 naloxone 合劑)也是麻醉用藥!很可惜,也可嘆,現在是精神科醫師的處方用藥!麻醉啊,麻醉,你都是為人作嫁,什麼時候,才能獨立啊!



Diacetylmorphine versus Methadone for the Treatment of Opioid Addiction.Volume 361:777-786 August 20, 2009 Number 8 NEJM

鑑於現有的戒毒防毒成效不彰,歐美現在更為前瞻開放,竟然是開放嗎啡注射,所謂堵不如導,與其讓其遁入地下流竄,不如讓其除罪化,以利於管理,人性黑暗的一面,不一定是邪惡,有時是愚,痴,貪,懦作祟,一點的同理心,可能更能解決問題!


thioamylal (citosol)

thiopental (pentothal)

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