歲月麻醉

Anesthesia,Joyful Life

顯示具有 antibiotics 標籤的文章。 顯示所有文章

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Prove-it Sepsis

H1N1新流感,讓我們見識到科技對抗疾病犀利的一面,快速篩檢30min,PCR 6 小時,那時沒有想到,怎麼這樣的技術,也可以運用到細菌感染的偵測。因為這次H1N1新流感主要是攻擊呼吸系統,併發肺炎感染是主要的表現,在治療方面,是否涵蓋細菌感染的課題就浮上檯面,目前實務上,還是使用十幾年前的作法,也就是Emperical antibiotics coverage- 經驗性抗生素用藥法,這樣的原始方式有其無奈的地方,一,所有的表徵,含影像學如胸x-ray,無法作微生物學的鑑別診斷,二,臨床醫師無法負荷需等到確定的實驗室檢驗結果才投藥。而這樣的結果,額外付出了抗生素濫用的代價,也應運產生感染這一個專門的學科。


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Atypical pneumonia coverage

Empirical antibiotics for CAP, 大部分的guideline建議需要atypical and typical pneumonia的抗菌涵蓋能力。有證據例嗎?沒有!


Empiric antibiotic coverage of atypical pathogens for community acquired pneumonia in hospitalized adults.Cochrane Database Syst Rev. 2008 Jan 23;(1):CD004418.


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什麼時候開始使用抗生素治療

When to Consider the Use of Antibiotics in the Treatment of 2009 H1N1 Influenza-Associated Pneumonia NEJM 2009 November 25th, 2009

1. 遵循社區感染性肺炎的綱領準則。

2.遵循臨床的徵象與檢查結果。

3.注意更新的疫情報導。

什麼時候要懷疑有二度細菌感染?

1. 流感
2. 二度發燒
3.細菌培養陽性
4. 胸部X光 Lobar consolidation
5. 白血球增高
6.晚期出現呼吸喘促症狀 (4-7 day)

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