歲月麻醉

Anesthesia,Joyful Life
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新流感重症患者


重症新流感的死亡率,14.3%,與未分亞型的甲型流感type A enfluenza  13.4%,其他亞型(季節流感,H3N2)16.2%,相差不遠,再與全美得住院死亡率5.6%,全體感染死亡率0.4~1.4% 同列來看,似乎這次的新流感並沒『比較』可怕!

比較有趣的是,住入加護病房另有97例11.3% type A enfluenza 病患,並沒有subtypine,原文內提到此點,認為這是此篇研究文章的一個瑕疵(limiting),並認為裡面可能會有一部分的假陰性新流感病患,所以嚴重度可能有『低估』的可能性。

番外篇:網路上找到的這個加護病房單位,可以說是最為『合格』的設計,一般人認為重症病房不需有與外界環境溝通的acess,譬如窗!這是外行人的無知,ICU psychosis就是這種不良設計的結果!

參考同篇報導:NEJ of Stupid 連結

原文連結:Critical Care Services and 2009 H1N1 Influenza in Australia and New Zealand. Published at www.nejm.org October 8, 2009

同期,另一篇美國的新流感住院分析文章:Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009 Published at www.nejm.org October 8, 2009 1/4住院患者會住入加護病房,住院死亡率為7%。比較有興趣的是,對於steroid的使用,大約有36%(1/3強)的病患,不過仔細去看,76%(3/4)有有使用steroid 的underlying disease,比如asthma, COPD等,所以,就這一點來看,雖然最新的ARDS使用steroid的薈萃分析favor 中小劑量的steroid使用,不過在這次新流感,由pneumonia引起的ARDS,外國人在使用上是傾向保守的!(不用)


Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: a systematic review and meta-analysis.Crit Care Med. 2009 May;37(5):1594-603.





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